Shirley Ann Manson FRSA is a Scottish musician and actress. She is the lead singer of the Scottish-American rock band Garbage. Manson gained media attention for her forthright style, rebellious attitude, and distinctive deep voice. For the majority of her career, Manson commuted between her home city of Edinburgh and the U.S. to record with Garbage, which originally formed in Madison, Wisconsin; she now lives and works primarily in Los Angeles, while maintaining a second home in Edinburgh.

Shirley Ann Manson was born in Edinburgh on 26 August 1966, the daughter of Muriel Flora (née MacKay) and John Mitchell Manson. Her father, a descendant from the fishing community of Northmavine, was a university lecturer, while her mother was a big band singer who had been adopted by a Lothian-based family at an early age and took on the family name MacDonald. Manson was named after an aunt, who was herself named after Charlotte Brontë's novel Shirley. She has two sisters: Lindy-Jayne who is two years older and Sarah who is two years younger. They were brought up in the Comely Bank and Stockbridge areas of Edinburgh in an old Victorian three-storey house. She attended Broughton High School and her childhood education was informed by the Church of Scotland (her father was her Sunday school teacher) until age 12.