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The problem, often not discovered until late in life, is that when you look for things like love, meaning, motivation, it implies they are sitting behind a tree or under a rock. The most successful people recognize, that in life they create their own love, they manufacture their own meaning, they generate their own motivation. For me, I am driven by two main philosophies, know more today about the world than I knew yesterday. And along the way, lessen the suffering of others. You'd be surprised how far that gets you.

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More Quotes by Neil deGrasse Tyson
There are as many atoms in each molecule of your DNA as there are stars in the typical galaxy. This is true for dogs, and bears, and every living thing. We are, each of us, a little universe.
Knowing how to think empowers you far beyond those who know only what to think.
The worst thing that ever happened to America was the 19th Amendment.
One of the biggest problems with the world today is that we have large groups of people who will accept whatever they hear on the grapevine, just because it suits their worldview—not because it is actually true or because they have evidence to support it. The really striking thing is that it would not take much effort to establish validity in most of these cases… but people prefer reassurance to research.
The molecules that comprise our body are traceable to the crucibles of the centers of stars.These atoms and molecules are in us because, in fact, the universe is in us. And, we are not only figuratively, but literally, stardust.
No one is dumb who is curious. The people who don't ask questions remain clueless throughout their lives.
In the end, it's the people who are curious who change the world.
To assert that the universe has a purpose implies the universe has intent. And intent implies a desired outcome. But who would do the desiring? And what would a desired outcome be? That carbon-based life is inevitable? Or that sentient primates are life's neurological pinnacle? Are answers to these questions even possible without expressing a profound bias of human sentiment? Of course humans were not around to ask these questions for 99.9999% of cosmic history. So if the purpose of the universe was to create humans then the cosmos was embarrassingly inefficient about it.
We are all connected; To each other, biologically. To the earth, chemically. To the rest of the universe atomically.
Claiming there is no other life in the universe is like scooping up some water, looking at the cup and claiming there are no whales in the ocean.