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The molecules that comprise our body are traceable to the crucibles of the centers of stars.These atoms and molecules are in us because, in fact, the universe is in us. And, we are not only figuratively, but literally, stardust.

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More Quotes by Neil deGrasse Tyson
Knowing how to think empowers you far beyond those who know only what to think.
One of the biggest problems with the world today is that we have large groups of people who will accept whatever they hear on the grapevine, just because it suits their worldview—not because it is actually true or because they have evidence to support it. The really striking thing is that it would not take much effort to establish validity in most of these cases… but people prefer reassurance to research.
To be scientifically literate is to empower yourself to know when someone else is full of bullshit.
The good thing about science is that it's true whether or not you believe in it.
To assert that the universe has a purpose implies the universe has intent. And intent implies a desired outcome. But who would do the desiring? And what would a desired outcome be? That carbon-based life is inevitable? Or that sentient primates are life's neurological pinnacle? Are answers to these questions even possible without expressing a profound bias of human sentiment? Of course humans were not around to ask these questions for 99.9999% of cosmic history. So if the purpose of the universe was to create humans then the cosmos was embarrassingly inefficient about it.
I know of no time in human history where ignorance was better than knowledge.
If your belief system is not founded in an objective reality, you should not be making decisions that affect other people.
Claiming there is no other life in the universe is like scooping up some water, looking at the cup and claiming there are no whales in the ocean.
The problem, often not discovered until late in life, is that when you look for things like love, meaning, motivation, it implies they are sitting behind a tree or under a rock. The most successful people recognize, that in life they create their own love, they manufacture their own meaning, they generate their own motivation. For me, I am driven by two main philosophies, know more today about the world than I knew yesterday. And along the way, lessen the suffering of others. You'd be surprised how far that gets you.
The Universe is under no obligation to make sense to you.